Dr. Linu Mathew

Dr. Linu Mathew (D.O.B 18. 09. 1974)

Associate professor

School of Biosciences

Mahatma Gandhi University

Priyadarshini Hills P O

Keralam-686 560

linubinoi@gmail.com
linumathew@@mgu.ac.in
Mob. 91- 9447505690

w/o Binoi Antony
Pichakapallil
Amalagiri P O
Kottayam-36
Keralam

Educational Qualifications

Degree Board Subjects Year Mark
(%)
Class/Rank
Ph.D.
in Biotechnology
MahatmaGandhi
University
2008
MSc Biotechnology Tamilnadu
Agricultural
University
Genetic Engineering,
Molecular Biology,
Enzymology, Biochemistry
1999 96 First Rank
with
distinction
 BSc. (Agriculture)  Kerala Agricultural
University
 Agronomy, Horticulture,
Plant Pathology,
Entomology, Genetics, Plant
Breeding, Extension,
Economics, Psychology
 1997  93  Distinction
 Pre- Degree  

Mahatma Gandhi
University

 Physics, Chemistry, Biology  1992  92   First Class
 S. S. L. C  State Board of Public
Examinations
 Basic Sciences, Social
Sciences and Languages
 1990  94  Distinction

Title of the thesis

Studies on the anticancer effects of Cassia fistula L.

Areas of Interests

Plant Tissue Culture, Molecular markers , molecular Phylogeny

Scholarships
1. CSIR. JRF and NET in the year 1998 December
2. D. B. T. Scholarship from 1997-1999
3. Kerala Agricultural University Merit scholarship from 1992-1996 (based on consistent and superior academic performance in each semester for all eight semesters)
4. Mahatma Gandhi University Merit Scholarship based on S. S. L. C. marks (from 1990-1992)

Merit Awards

M. S. Swaminathan Award for the best student in Biotechnology for the year 1999 of Centre for Plant Molecular Biology, TNAU (for highest OGPA)

Professional Achievements
Mebership in Academic Bodies

1.Member (Subject Expert for Biotechnology)Academic council.MG University
2.Member Expert committee for UG biotechnology of MG University Kerala. India
3.Member Expert committee for PG biotechnology of MG University. Kerala. India
4.Member Board of Studies of Biotechnology St Berchman’s college (autonomous).Chanaganassery. Kottayam.   Kerala. India
5.Member Board of Studies of botany Sacred heart College (autonomous)Thevara. Ernakulum. Kerala. India
6.Member Kerala Academy Of Sciences

My Teaching
a) Teaching Experience

1.Teaching Genetics, Genetic Engineering, Plant and Animal Biotechnology at PG and M Phil level since 26 March,   2001 till date. (17 years experience)
2.Teaching Biological techniques for Ph D course work from 2012 onwards

3.Course coordinator for P h D course work for 2012 Ph D admission in the School of Biosciences
4.Course coordinator for I MSc Biosciences in the School of Biosciences 2015-2016

b) E content development
1. SLO on Animal Cloning
http://www.mguniversity.edu/index.php?option=com_content&view=article&id=1713&Itemid=1845

My research

A ) Publications
a) Papers Published

1) Linu Mathew, R. Chandra Babu, J. Souframanien, P. Chezhian, P.Shanmugasundaram, P. Nagarajan and S. Sadashivam, DNA Polymorphism among Rice(Oryza sativa L. ) accessions differing in draught tolerance, J. Plant Biol, Vol 27 (2) pp 145-152 (2000)

2 )Linu Mathew, Sankar Sashidhar, Chemopreventive potential of methanol extract of stem bark of Cassia fistula in mice, Journal of Pharmacognosy and herbal ormulations,vol2 , (ISSN 2229-6840)(2012)

3) Reshma John, Siji Raju, Jyothis Mathew, Linu Mathew, Endophytic associations in Achyranthes aspera L. Journal of Science, Technology And Management, Vol 04,No2,9-13(2012)

4.) Rashmi PA, Reshma John and Linu Mathew.2012. Isolation and characterisation of vasicine from in vitro Cultures of Justicia adhatoda, International journal of Pharma and Bio Sciences 3( 3)/B58-64.ISSN.0975-6299 (SJR = 0.274 )

5) Linu Mathew, Rashmi P A.2012.Development of salinity resistant somaclones of Justicia adhathoda- an important medicinal plant with bronchodilatory effect. Research journal of pharmaceutical, biological and chemical sciences 3 (3):132. ISSN: 0975-8585 (SJR= 0.19)

6) Rashmi P A Linu Mathew, 2012 .The effect of elicitors on the production of vasicine from Justicia adhathoda L cell suspension cultures. 3, (10).October, 2012.The international journal of pharmaceutical science and research (Impact factor.0.533)

7) Mathew Linu, Shashidhar Shankar In vitro cytotoxic activity of methanolic extract of stem bark of Cassia fistula L. . 2012. Research journal of Biotechnology.7 (4) 141- 148(SJR= 0.16)

8) Rashmi P A, Linu Mathew.2012. Antimicrobial activity of leaf extract of Justicia adhathoda in comparison with vascicine. Asian Pacific journal of Tropical Biomedicine. 2012. S1556-S1560 (SJR= 0.57)

9) Aneesha Devassy, Raj Kumar, P. P. Shajitha, Reshma John, K. G. Padmakumar, V. S. Basheer, A. Gopalakrishnan & Linu Mathew (2015): Genetic identification and phylogenetic relationships of Indian clariids based on mitochondrial COI sequences,MitochondrialDNA,EarlyOnline:142015Taylor&Francis.DOI:10.3109/19401736.2015.1
079901,http://dx.doi.org/10.3109/19401736.2015.1079901 Impact factor 1.7 (Thomson Reuters)

10) Molecular Phylogeny of Balsams (Genus Impatiens) Based on ITS Regions of Nuclear Ribosomal DNA Implies Two Colonization Events in South India, P. P. Shajitha, N. R. Dhanesh, P. J. Ebin, Laly Joseph, Aneesha Devassy, Reshma John, Jomy Augustine, Linu Mathew. Journal of Applied Biology and Biotechnology ISSN Print:2455-7005 ISSN Online: 2347-212X Journal of Applied Biology & Biotechnology Vol.4 (06), pp. 001-009, Nov-Dec, 2016 Available online at http://www.jabonline.inDOI: 10.7324/JABB.2016.40601

11. A Combined Chloroplast atpB-rbcL and trnL-F Phylogeny Unveils the Ancestry of Balsams (Impatiens spp.) in the Western Ghats of India. P. P. Shajitha · N. R. Dhanesh ·P. J. Ebin · Joseph Laly · Devassy Aneesha · John Reshma · Jomy Augustine · Mathew Linu. DOI: 10.1007/s13205-016-0574-8 3Biotech Springer (published) Impact factor.
1(Thomson Reuters)

12.John Reshma, Mathew Linu, Endophytic Fungal Assemblage in Achyranthes aspera Linn. Revealed by Internal Transcribed Spacer Region of Nuclear Ribosomal RNA genes" (DOI:10.1007/s13205-017- 0748-z) 3Biotech (Springer) Impact factor. 1.4 (Thomson Reuters)

13. Hairy root cultures of Achyranthes aspera Linn. as a novel route for the production of 20-hydroxyecdysone; Reshma John, Shajitha PP, Aneesha Devassy, Linu Mathew; Acta Physiologiae Plantarum (Springer) Thomson Reuters Impact Factor 1.4 DOI:10.1007/s11738-017- 2555-x

14. Effect of elicitation and precursor feeding on accumulation of 20-hydroxyecdysone in Achyranthes aspera Linn. cell suspension cultures; Reshma John, Shajitha PP, Aneesha Devassy, Linu Mathew; Physiology and Molecular Biology of Plants (Springer) DOI: 10.1007/s12298-018- 0506-7 (Published) Thomson Reuters Impact Factor 0.9

b) Paper \poster presented at conferences

1) Micropropagation and secondary metabolite isolation from Adahthoda vassica Nees,Rashmi PA, Reshma John, Linu Mathew ,Kerala women,s science congress August 2010

2) Endophytic associations in Neem Plants (Azadirachta indica A juss.) in Kerala Preethy MR, Jyothis Mathew, Linu Mathew, Kerala Womens Science Congress August 2010

3) Genetic variation in populations of Clarias dussumieri dussumieri in different geographical locations of Kerala Aneesha Devassi, Smitha Thomas, Linu Mathew World congress on biotechnology, 2011

4) Genetic variation in populations of Monochoria vaginalis in different geographical areas of coastal Kerala, Smitha Thomas. K., Aneesha Devassy , Linu Mathew, World congress on biotechnology, 2011

5) Endophytic fungal diversity and colonization in Achyranthes aspera Linn. Reshma John, Siji Raju, Jyothis Mathew, Liinu Mathew 24th Kerala Science Congress, KSCSTE,Thiruvanthapuram Jan 2012

6) Studies on endophytic associations in Achyranthes aspera . Reshma John, Siji Raju,Jyothis Mathew, Liinu Mathew, International congress and symposium in plant sciences,at MACFAST ,Thiruvalla, Kerala 2011

7) Poster presentation in International congress and symposium in plant sciences, at MACFAST, Thiruvalla, Kerala 2011

8) Molecular charecterisation of three species of Clarias (pisces:siluriformes:claridae) using RAPD markers, Aneesha Devassy, Linu Mathew, Padmakumar K.G,Gopalakrishnan. A, Basheer,V.s,raj Kumar, Second Indian Biodiversity
congress(IBC2012 December)

9) Biodiversity of endophytic fungi in Ppteris confusa and Pteris longifolia(pteridaceae)through nuclear rDNA ITS analysis. Thushara Susan Sabu, Reshma John,Linu Mathew. 2012. National Biodiversity Congress.Thiruvananthapuram

10) Molecular phylogenetic relationship among endemic balsms of Western Ghats using chloroplast atpb-rbcl spacer sequences. Shajitha P.P, Dhanesh N. R, Aneesha Devassy,Jomy Augustine, Linu Mathew. 2012. National Biodiversity Congress.Thiruvananthapuram

11) Evaluation of endophytic fungal diversity n in Achyranthes aspera based on rDNA ITS analysis.Reshma John, Rashmi P A, Linu Mathew. 2012. National Biodiversity Congress.Thiruvanthapuram.

12) Molecular phylogenetic relationship among endemic balsms of Western Ghats using chloroplast atpB-rbcL spacer sequences. Shajitha P.P, Dhanesh N. R, Aneesha Devassy,Jomy Augustine, Linu Mathew. 2013. International conference on Plant Biosystematics ICPB 2013. St. Berchmans College. Kottayam. Kerala

13) Callus induction and in vitro propagation of Achyranthes aspera Linn.Reshma John,Rashmi P A, Linu Mathew.2013.International conference on Plant Biosystematics ICPB 2013.St. Berchmans College. Kottayam. Kerala

14) Indirect organogenesis and histological analysis of organogenic and nonorganogenic calli obtained from in vitro cultures of Justicia adhathoda L. Rashmi P A, Linu Mathew.2013. International conference on Plant Biosystematics.ICPB 2013.St.Berchmans College.Kottayam.Kerala

15) Genetic identification and phylogenetic relationship of three catfishes seen in India based on mitochondrial CO1 and 16 S Ribosomal RNA partial sequences, Aneesha devassy, Linu Mathew, K.G.Padmakumar,A. Gopalakrishnan,V. Basheer, V. S.Rajkumar. 2013. 25th Kerala Science Congress. Thiruvananthapuram

16) DNA polymorphisms among Justicia adahthoda L somaclones differing in vascicine production, Rashmi PA, Linu Mathew, 2013. 25th Kerala Science Congress,Thiruvananthapuram

17) Endophytic Fungal Diversity in Cheilanthes tenuifolia (Fa.Pteridaceae) Thuhara Susan Sabu, Reshma John , Linu Mathew, 8th International conference on climate change, territorial classification & socio- economic Crisis, April 2013 , Bharathidasan University, Thiruchirapally, Tamil Nadu, India

18) Genetic diversity analysis of four samples of Clarias dussumieri from Periyar Basin Aswathi Ramachandran, Aneesha Devassy, Dhanesh N. R., Padmakumar K.G.,Gopalakrishnan A. and Linu Mathew (26th kerala science Congress)

19) Isolation, characterization and analysis of multiple bioactivities of Trametes menziesii: A potent endophyte from Pteris longifolia Thushara Susan Sabu, Dayana Joseph, Josna T. Joy , Rashmi P. A. and Linu Mathew (26th Kerala Science Congress)

20) Genetic diversity of endophytic Colletotrichum spp in Achyranthes aspera Linn.,Reshma John, Linu Mathew Sweshi Sscience Congress 2014

21) Bioactive properties of Ethyl Acetate fraction of Marine Bacteria Staphylococcus warneri, Nithin T. U., Keerthi T. R. and Linu Mathew (26th Kerala Science Congress)

22) Callus induction and multiple shoot regeneration from nodal explants of Achyranthes aspera Linn . Reshma John, Shajitha P P, Aneesha Devassi, Linu Mathew. Proceedings of the national seminar on plant wscience technology for sustainable world(February 25-26 2016 ,NIPST , MG University,ISBN :978-81-930000-8-3. pp 79-82 1st prize in Oralpresentation

23) Molecular phylogeny of balsams(Genus Impatiens) based on chloroplast atpB- rbcL region indicates two colonization events by the balsam ancestors. PP Shajitha , NR dhanesh, P J Ebin, Laly Joseph, Aneesha devassy, Reshma John, Jomy Augustine , Linu Mathew. Proceedings of the national seminar on Plant Science Technology for
Sustainable world(February 25-26 2016 ,NIPST , MG University,ISBN :978-81-930000-8-3. pp 83-86

24) Molecular phylogeny of balsams based on combined sequences of nuclear ITS, Def1 and Def 2 regions; Shajitha PP, Jomy Augustine, Linu Mathew; 29th Kerala science congress proceedings pp. 229-234

25) Mosquito larvicidal activity of phytoecdysteroid (20- hydroxyecdysone)against Adesalbopictus larvae. Rshma John and Linu Mathew. National Seminar on Recent Trend in Applied Life Sciences. March 15-16, School of Biosciences, M G University. ISBN 978-93-80419-30-5 pp 33-34 1st prize in Oral presentation

26)Enhancing the production of vasicine from cell suspension cultures of Justicia adhatoda L by supplementing L tryptophan,L –aspartic Acid. Vinaya Chandran, Shahena S and Linu Mathew, National Seminar on Recent Trend in Applied Life Sciences.March 15-16, School of Biosciences, M G University,ISBN 978-93-80419-30-5 pp 49-50

c) Book Chapter published
1) Biological Effects of Ecdysteroids and Their Non Steroidal Agonist Bisacylhydrazines– A Review, Reshma John, Rashmi P.A, And Linu Mathew, Biotechnology Vol. 7: pp 389- 409, Drug Discovery, ISBN 1-62699-022-0, Studium Press, Houston, USA. .

2) Molecular charecterisation of three species of Clarias(pisces:siluriformes:claridae) using RAPD markers, Aneesha Devassy, Linu Mathew, Padmakumar K.G ,Gopalakrishnan. A, Basheer,V.S, Raj Kumar(eds Bijukumar A, Rajendran C K, Peethambaran C K), Perspectives on Biodiversity of India, Vol.1: pp 197-201, ISBN 978-81-929896-0-0, Published by Centre for Innovation in Science and Social Action, Trivandrum , Kerala

3)Cloning of Animals: Techniques And Applications, Linu Mathew, In e –learning Instructional designs for Short Learning Objects (Eds. R. Vijayakumar, Sajimon Abraham, Sajna Jaleel) ISBN 978-93- 80419-29- 9 published by Department of Printingand Publishing M G University . Pp.47-51. 2017

4) Multiple shoot induction and production of insect moulting hormone 20-Hydroxyecdyone from the callus cultures of medicinal plant Achyranthes aspera L.resham John. Shajitha PP, Aneesha devassy, Linu Mathew. In Plant Science Technology for Sustainable Development (Eds. Jisha MS, Maghesh Rajan. M, Aju K asok ) ISBN 978-93- 82845-00- 3. Pp. 85-99. 2017

5) Molecular Phylogeny of Balsams (genus Impatiens) Based on Chloroplast atpB-rbcL spacer region. PP Shajitha , NR Dhanesh, P J Ebin, Laly Joseph, Aneesha devassy,Reshma John, Jomy Augustine , Linu Mathew. In. Plant Science Technology forSustainable Development. (Eds. Jisha MS, Maghesh Rajan. M, Aju K asok ) ISBN 978-693-82845- 00-3. Pp. 100-113. 2017

d) NCBI GenBank Accessions
More than 200 accessions

e) Ph D thesis supervised and awarded
1. In vitro propagation studies of Justicia adhathoda L. a medicinal plant with bronchodilatory effect ( Rashmi P A)

2.Production of 20- hydroxyecdysone from in vitro cultures of Achyranthes aspera Linn (Reshma John)

3.Molecular phylogenetic relationships among Impatiens L. (Balsaminaceae) Using Chloroplast And Nuclear regions (Shajitha PP)

4.Phylogeny of Indian clariids and population genetic structure of Clarias dussumieri using molecular markers (Aneesha Devassy)

f) M Phil theses supervised

1) Isolation and Charecterisation of Vascine from Callus and Suspension cultures of Adhathoda vasica Nees.( Rasmi    P A)
2) Isolation of phytoecdysteroid from the suspension cultures of Achyranthes aspera Linn.( Reshma John)

3) Studies on the endophytic Associations in neem (Azadirachta indica A.Juss) (Preethi M R)

4) Studies on the endophytic associations in Achyranthes aspera (Siji Raju)

5) Endophytic Associations in three fern species belonging to Fa. Pteridaceae(Tushara Susan Sabu)

6) Molecular Phylogeny of cucurbitaceae :- A preliminary Study (Maya Rajan)

7) Molecular evolution and phylogenetic utility of K –domain of AP3/DEF paralogues of Impatiens (Balasaminaceaae) of Southern Western Ghats (Shinsy P)

8) Enhancing the production of vasicine from cell suspension cultures of Justicia adhatoda L. by supplementing L-Tryptophan, L- Aspartic acid (Vinaya Chandran)

g) MSc projects supervised (number)
Fourteen

h) Invited lectures
Four

1. Seminar on Modern trends in molecular biology, St Thomas College Kozhencherry

2. UGC sponsored national seminar on Basic and Advanced Biochemical Techniques Relevance in Interdisciplinary Research scenario BK College for Women Kottayam,

3. Utilization , Management and conservation of Medicinal plants UGC sponsored National Seminar on Utilization , Management and conservation of Medicinal plants, BK college for women

4. Databases and database searching, Seminar on Bioinformatics and Biotechnology, Cochin College

C) Workshops and Seminar attended

1) Workshop on recombinant DNA Technology conducted by CFBTR, Madurai.(21-12-2002 to 31-02-2002)

2) 3 Day Seminar cum Workshop on Animal Cell Culture in School of Medical Education, M. G. U., Gandhi Nagar, from 03-11-03 to 05-11-03

3) UGC Sponsored orientation Course from 14-10-04 to 10-11-04 at Bharathiar University

4) Workshop on Statistical Applications in Research Studies By School of Environmental Sciences, M. G. U. from 20-07-04 to 25-07-04

5) UGC Sponsored Refresher Course on Life Sciences by CUSAT from 19-02-07 to 10-03-07

6) National Seminar on Biosciences from 14-02-07to 15-02-07 organized by School of Biosciences, M. G. U.

7) National seminar series in connection with Birth Bicentenary of Charles Darwin) at School of Biosciences 2009 (convened )

8) National seminar on GM Crops and food security at KSCSTE, Trivandrum Kerala 2009

9) National seminar on Role of women in climate change at KSCSTE Thiruvananthapuram Jan 2010

10) Kerala Women’s Science Congress, August 2010

11) Workshop on Plant DNA barcoding at CMS College, Kottayam, MG University December 2011

12) National Seminar on Life style and Diseases at School of Biosciences, M G University 2012

13) Molecular phylogeny workshop at IISc Bangalore from August 1-5, 2014

14) DBT sponsored workshop on Molecular biology techniques in Microbiology,CFTRI Mysore15 days excluding holidays from Sept 2-19, 2014

15) Workshop on plate tectonics: recent advances from Southern India and East Antarctica Geology Department, University Of Kerala.

16) National workshop on Mass Spectroscopy at Interuniversity Centre for instrumentation , Mahatma Gandhi University, Kerala

17) Training cum Workshop on Molecular docking and drug designing at School of Biosciences , M G University

18) National Seminar on Plant Science and Technology(Feb 26 th &27 th 2016) NIPST
MG university Joint Convenor

19) Bodhani (17 th &18 th 2016 March) School of Biosciences , M G University Joint
Convenor

20) Seminar cum workshop on Empowering Teachers in Mentoring and Student
counseling (29 th , 30 th & 31 st March 2016) School of Behavioral Sciences. MG
University

21) Seminar on NAAC accreditation Process School of Pure and Applied Sciences
12 th April 2016

22) Faculty development Programme on E learning and E- Content development
held by DCDC MG University 16th- 30 th January 2017

23) National seminar on Recent trends in Appied life sciences 15 th and 16 th march
2017 School of Biosciences MG University Joint Convenor

24) National seminar Ecotechnological Perspectives for Sustainable Development
27 th and 28 th july 2027 school of Biosciences MG University Joint Convenor

D) Ongoing Research Programmes

1) Molecular Phylogeny of Vernonia spp

2) Anticancer effects of wild Mushrooms

3) Anticancer effects of cultivated tuber crops

4) Allelopathic effects of wedelia Spp

5) In vitro culture studies of Vernonia anthelmintica

E) Externally Funded Projects
1) Principal investigator in the KSCSTE funded major research Project Barcoding and genetic diversity Analysis of Clarias Spp of Kerala (Completed)

2) Principal investigator in the UGC funded major research Project Production of Phytoecdysteroids from in vitro cultures of Achyranthes aspera Linn (completed)

Declaration
The information give above are true to the best of my knowledge and belief.

                                                                                                                                                                       LINU MATHEW